Low profile refers to the difference in height from the heel of a shoe to the toe of a shoe.  A low profile shoe means that the heel and toe height are more even which allows you to land more on your mid foot.  Low profile can also refer to the amount of cushioning in a shoe.  Heavy training shoes will often have very thick cushioning or a higher profile.  Race flats will often have less cushioning, be lighter and have a lower profile.

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